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All about muscular dystrophy types of muscular dystrophy causes of Duchenne muscular dystrophy symptoms of Duchenne muscular dystrophy causes of Becker's muscular dystrophy symptoms of Becker's muscular dystrophy causes of limb-girdle muscular dystrophy symptoms of limb-girdle muscular dystrophy causes of facioscapulohumeral muscular dystrophy symptoms of facioscapulohumeral muscular dystrophy causes of myotonic dystrophy symptoms of myotonic dystrophy diagnosis of muscular dystrophy treatment for muscular dystrophy

What causes myotonic dystrophy?

Myotonic dystrophy can occur in both sexes and is the most common form of adult muscular dystrophy, with symptoms often starting in adolescence. Myotonic dystrophy is caused by an inherited gene defect, called a "triple repeat," on chromosome 19. The defective gene has not been positively identified as of early 1998. The triple repeat probably affects neighboring genes as well. Involvement of more than one gene would explain the multisystem effects of DM. The gene is inherited in an autosomal dominant pattern. In this pattern, one copy of the gene inherited from an affected parent is enough to cause the disease in the offspring. The chance of inheriting the DM gene from an affected parent is 50% for each child. This percentage is not changed by results of other pregnancies. The relation between the affected gene and the resulting myotonia, or inability to relax muscles, is not yet understood. The disease somehow blocks the flow of electrical impulses across the muscle membrane. Without proper flow of charged particles, the muscle cannot return to its relaxed state after it has contracted.

More information on muscular dystrophy

What is muscular dystrophy? - Muscular dystrophy is a group of inherited diseases that are characterized by weakness and wasting away of muscle tissue.
What types of muscular dystrophy are there? - There are nine types of muscular dystrophy including Duchenne muscular dystrophy, Becker muscular dystrophy, facioscapulohumeral muscular dystrophy.
What causes Duchenne muscular dystrophy (DMD)? - Duchenne muscular dystrophy is a rapidly progressive form of muscular dystrophy. It is caused by a defective gene.
What're the symptoms of Duchenne muscular dystrophy? - Symptoms of Duchenne muscular dystrophy include progressive muscle weakness of the legs and pelvis, mental impairment or heart problems.
What causes Becker's muscular dystrophy? - Becker muscular dystrophy is a type of dystrophinopathy which include a spectrum of muscle disease caused by mutations in the DMD gene.
What're the symptoms of Becker's muscular dystrophy? - Symptoms of Becker-type muscular dystrophy are similar to those of Duchenne dystrophy, but they are milder and begin later.
What causes limb-girdle muscular dystrophy? - Limb-girdle muscular dystrophy is an inherited disorder, it may be inherited as a dominant, recessive, or X-linked genetic defect.
What're the symptoms of limb-girdle muscular dystrophy? - Symptoms of limb-girdle muscular dystrophy include progressive muscle weakness in the shoulders and hips, together with breathing problems.
What causes facioscapulohumeral muscular dystrophy? - Facioscapulohumeral muscular dystrophy involves progressive muscle weakness and loss of muscle tissue.
What're the symptoms of facioscapulohumeral muscular dystrophy? - Symptoms of facioscapulohumeral muscular dystrophy may begin during infancy, late childhood, or early adulthood.
What causes myotonic dystrophy? - Myotonic dystrophy is caused by an inherited gene defect. Myotonic dystrophy is the most common form of adult muscular dystrophy.
What're the symptoms of myotonic dystrophy? - Symptoms of myotonic dystrophy include muscle weakness and wasting, cataracts, heart problems, constipation and other digestive problems.
How is muscular dystrophy diagnosed? - Diagnosis of muscular dystrophy involves a medical history and physical exam to determine the distribution of symptoms and to rule out other causes.
What's the treatment for muscular dystrophy? - Treatments for muscular include decreased mobility and dexterity, contractures, scoliosis, heart defects, and respiratory weaknesses.
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