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All about muscular dystrophy types of muscular dystrophy causes of Duchenne muscular dystrophy symptoms of Duchenne muscular dystrophy causes of Becker's muscular dystrophy symptoms of Becker's muscular dystrophy causes of limb-girdle muscular dystrophy symptoms of limb-girdle muscular dystrophy causes of facioscapulohumeral muscular dystrophy symptoms of facioscapulohumeral muscular dystrophy causes of myotonic dystrophy symptoms of myotonic dystrophy diagnosis of muscular dystrophy treatment for muscular dystrophy

What causes limb-girdle muscular dystrophy?

Limb-girdle muscular dystrophy is typically an inherited disorder, though it may be inherited as a dominant, recessive, or X-linked genetic defect. The result of the defect is that the muscles cannot properly form the proteins needed for normal muscle function. Several different proteins can be affected, and the specific protein that is absent or defective identifies the specific type of muscular distrophy. The limb girdle muscular dystrophies are divided into two main groups, depending on the way they are passed on in families. On this basis, they are grouped into autosomal recessive or type 2 LGMD and the much rarer group of autosomal dominant or type 1 LGMD. They can be further subdivided on the basis of more complicated gene or muscle protein tests which may tell us exactly where the problem lies. Approximately 90% of limb girdle muscular dystrophies are inherited as an autosomal recessive disorder. For someone to have one of these conditions they have to have two faulty copies of the gene responsible. All of our genes come in pairs, one from our mother and one from our father. If someone has an autosomal recessive type of limb girdle muscular dystrophy both of their parents must be carriers.

More information on muscular dystrophy

What is muscular dystrophy? - Muscular dystrophy is a group of inherited diseases that are characterized by weakness and wasting away of muscle tissue.
What types of muscular dystrophy are there? - There are nine types of muscular dystrophy including Duchenne muscular dystrophy, Becker muscular dystrophy, facioscapulohumeral muscular dystrophy.
What causes Duchenne muscular dystrophy (DMD)? - Duchenne muscular dystrophy is a rapidly progressive form of muscular dystrophy. It is caused by a defective gene.
What're the symptoms of Duchenne muscular dystrophy? - Symptoms of Duchenne muscular dystrophy include progressive muscle weakness of the legs and pelvis, mental impairment or heart problems.
What causes Becker's muscular dystrophy? - Becker muscular dystrophy is a type of dystrophinopathy which include a spectrum of muscle disease caused by mutations in the DMD gene.
What're the symptoms of Becker's muscular dystrophy? - Symptoms of Becker-type muscular dystrophy are similar to those of Duchenne dystrophy, but they are milder and begin later.
What causes limb-girdle muscular dystrophy? - Limb-girdle muscular dystrophy is an inherited disorder, it may be inherited as a dominant, recessive, or X-linked genetic defect.
What're the symptoms of limb-girdle muscular dystrophy? - Symptoms of limb-girdle muscular dystrophy include progressive muscle weakness in the shoulders and hips, together with breathing problems.
What causes facioscapulohumeral muscular dystrophy? - Facioscapulohumeral muscular dystrophy involves progressive muscle weakness and loss of muscle tissue.
What're the symptoms of facioscapulohumeral muscular dystrophy? - Symptoms of facioscapulohumeral muscular dystrophy may begin during infancy, late childhood, or early adulthood.
What causes myotonic dystrophy? - Myotonic dystrophy is caused by an inherited gene defect. Myotonic dystrophy is the most common form of adult muscular dystrophy.
What're the symptoms of myotonic dystrophy? - Symptoms of myotonic dystrophy include muscle weakness and wasting, cataracts, heart problems, constipation and other digestive problems.
How is muscular dystrophy diagnosed? - Diagnosis of muscular dystrophy involves a medical history and physical exam to determine the distribution of symptoms and to rule out other causes.
What's the treatment for muscular dystrophy? - Treatments for muscular include decreased mobility and dexterity, contractures, scoliosis, heart defects, and respiratory weaknesses.
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