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Bone diseases

Fibrous dysplasia
Fibrous dysplasia is a skeletal developmental anomaly of the bone-forming mesenchyme that manifests as a defect in osteoblastic differentiation and maturation. Fibrous dysplasia is usually evident during childhood, and the bone lesions usually stop developing at puberty. Fibrous dysplasia is thought to be a congenital disorder.
Osteomalacia involves softening of the bones caused by a deficiency of vitamin D or problems with the metabolism of this vitamin. Osteomalacia means soft bones. Like osteoporosis, osteomalacia weakens the bones and makes bones more likely to break. Osteomalacia is a condition in which the bones become soft.
Rickets is an abnormal bone formation in children resulting from inadequate calcium in their bones. This lack of calcium can result from inadequate dietary calcium, inadequate exposure to sunshine (needed to make vitamin D), or from not eating enough vitamin D. Rickets is a failure to mineralize bone.
Osteomyelitis is infection of the bone, usually by a pus-forming bacteria. All bacterial osteomyelitis starts as acute infection. Osteomyelitis may occur as a result of a bacterial bloodstream infection, sometimes called bacteremia, or sepsis, that spreads to the bone. Many different types of bacteria and viruses can cause osteomyelitis.
Avascular necrosis (osteonecrosis)
Avascular necrosis of bone (AVN) (or aseptic necrosis or osteonecrosis), is a disease that results from poor blood supply to an area of bone causing bone death. Avascular necrosis of bone is a disorder in which an avascular (lacking in blood supply) area of bone undergoes necrosis (dies). Pain associated with avascular necrosis is often severe and unrelenting.
Osteoporosis is a disease of bone in which the amount of bone is decreased and the strength of trabecular bone is reduced, cortical bone becomes thin and bones are susceptible to fracture. Osteoporosis is condition that features loss of the normal density of bone. Osteoporosis occurs most often in older people and in women after menopause.
Paget's disease of the bone
Paget's disease of the bone is a chronic bone disorder in which bones become enlarged and deformed. Bone may become dense, but fragile, because of excessive breakdown and deformation of bone. Paget's disease can cause bones to weaken and may result in bone pain, arthritis, bone deformities and fractures.

Topics in bone, joint, and muscle disorders

Bone diseases
Bone tumors
Bone cancer
Muscle diseases
Spine (neck and back) disorders
Dupuytren's contracture
Plantar fasciitis
Rheumatoid arthritis
Juvenile rheumatoid arthritis
Septic arthritis (infectious Arthritis)
Psoriatic arthritis
Reiter's syndrome (reactive arthritis)
Ankylosing spondylitis
Gout (gouty arthritis)

All information is intended for reference only. Please consult your physician for accurate medical advices and treatment. Copyright 2005,, all rights reserved. Last update: July 18, 2005